Body & HealthFact
Your brain has its own border control with bouncers.
The blood–brain barrier arises because the cells lining brain capillaries are sealed by tight junctions, wrapped by astrocyte end-feet and pericytes. Oxygen and CO2 diffuse through; glucose and amino acids need transporters. More than 98 percent of all small-molecule drugs never get in at all.
Useful: Explains why many substances that work in a dish never reach the brain.
Source: en.wikipedia.org